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Получение органоидов желез змеиного яда для производства яда in vitro

Получение органоидов желез змеиного яда для производства яда in vitro

 

Ежегодно более 400000 человек страдают от побочных эффектов от укусов ядовитых змей. Однако змеиный яд также является богатым источником биоактивных молекул с известным или потенциальным терапевтическим применением. Самым распространенным методом получения яда является «доение» змей вручную. Более безопасные альтернативные методы производства яда облегчили бы производство как противоядия, так и новых терапевтических средств.

Этот протокол описывает генерацию, обслуживание и избранные применения органоидов железы змеиного яда. Органоиды ядовитых желез змей – это трехмерные модели культур, которые могут быть получены в течение нескольких дней из тканей эмбриональных или взрослых ядовитых желез нескольких видов змей и могут сохраняться в течение длительного времени (некоторые органоиды мы культивировали более 2 лет). Мы успешно использовали этот протокол с железами эмбрионов поздних стадий и недавно умерших взрослых змей. Клеточная неоднородность ядовитой железы сохраняется в органоидах, и состав клеточного типа может контролироваться путем изменения состава среды.

Мы подробно описываем, как получить и выращивать органоиды, как диссоциировать их на отдельные клетки и как криоконсервировать и дифференцировать их в органоиды, продуцирующие токсины. Мы также предоставляем рекомендации по полезным последующим анализам, в частности количественной ПЦР в реальном времени, массовому и одноклеточному секвенированию РНК, иммунофлуоресценции, иммуногистохимии, флуоресцентной гибридизации in situ, сканирующей и просвечивающей электронной микроскопии и генной инженерии. Этот пошаговый протокол может выполняться в любой лаборатории с оборудованием для культивирования тканей и позволяет исследовать продукцию яда, дифференциацию и клеточную гетерогенность.

 

Обнаружение SRAS-CoV-2 в поликлиниках и государственных учреждениях во время пандемии COVID19

Передача вируса короны 2 тяжелого острого респираторного синдрома (SARS-CoV-2) может происходить воздушно-капельным путем в дополнение к зараженным поверхностям и объектам. В больницах несколько исследований подтвердили, что SRAS-CoV-2 может загрязнять поверхности и медицинское оборудование, особенно в больницах, предназначенных для пациентов с COVID-19. Целью этого исследования было выявление загрязнения рук, предметов и поверхностей в изоляторах, а также в амбулаторных условиях больниц и поликлиник. Загрязнение окружающей среды общедоступных поверхностей в общественных местах также исследовалось во время активной пандемии COVID-19.

Мазки также брали с поверхностей, подверженных частым прикосновениям, в амбулаторных учреждениях. Случайные мазки также были взяты из общественных магазинов, аптек, пекарен, бакалейных товаров, банкнот и банкоматов. Образцы были проанализированы на наличие SARS-CoV-2 с использованием ПЦР в реальном времени. В региональной референс-больнице COVID-19 только 3 из 20 образцов оказались положительными на РНК SARS-CoV-2. Мазки с рук от SARS-CoV-2 пациентов в изоляторах иногда были положительными на вирусную РНК. В поликлиниках дверные ручки были наиболее загрязненными поверхностями. Стоматологические кресла, раковины, клавиатуры, офтальмоскопы и лабораторное оборудование также были загрязнены.

Хотя в магазинах и общественных учреждениях не было обнаружено положительных мазков, выборочные мазки из банкоматов дали положительный результат на SARS-CoV-2. Несмотря на то, что внимание было перенесено на палаты и больницы с коронавирусом COVID-19, больше внимания необходимо уделять обеззараживанию поверхностей, к которым часто прикасаются, в медицинских учреждениях, используемых пациентами, у которых не диагностирован COVID-19. Кроме того, общественные поверхности с высокой степенью касания, такие как банкоматы, требуют дополнительных процедур дезинфекции для ограничения передачи инфекции. Эта статья защищена авторским правом. Все права защищены.

Получение органоидов желез змеиного яда для производства яда in vitro

Системы CRISPR для диагностики COVID-19

Появление нового коронавируса 2019 года (COVID-19) впервые было замечено в декабре 2019 года, который быстро распространился и стал глобальной пандемией. Количество случаев COVID-19 и связанная с ним смертность вызывают серьезную обеспокоенность во всем мире. Ранняя диагностика вирусной инфекции, несомненно, позволяет быстро вмешиваться, управлять заболеванием и существенно контролировать быстрое распространение болезни.

В настоящее время стандартным подходом к диагностике COVID-19 во всем мире является тест RT-qPCR; однако ограниченный доступ к наборам и связанным с ними реагентам, потребность в специализированном лабораторном оборудовании и потребность в высококвалифицированном персонале привели к замедлению обнаружения. В последнее время разработка кластерных диагностических систем на основе регулярных промежуточных коротких палиндромных повторов (CRISPR) изменила молекулярную диагностику. Такие преимущества системы CRISPR, как скорость, точность, специфичность, сила, эффективность и универсальность, вдохновили исследователей на разработку диагностических и терапевтических методов на основе CRISPR. С глобальной вспышкой COVID-19 различные группы приступили к разработке и разработке диагностических и терапевтических программ на основе эффективной системы CRISPR.

Системы диагностики COVID-19 на основе CRISPR обладают такими преимуществами, как высокая скорость обнаружения (т. Е. 30 минут от необработанного образца до получения результата), высокая чувствительность и точность, портативность и отсутствие необходимости в специализированном лабораторном оборудовании. Здесь мы рассматриваем современные исследования по выявлению COVID-19 на основе системы CRISPR.

Apo AI Antibody (Biotin)

abx023213-1ml 1 ml
EUR 899
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Apolipoprotein A-I (Apo AI) Antibody

abx022325-1mg 1 mg
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Apolipoprotein A-I (Apo AI) Antibody

abx022326-1mg 1 mg
EUR 648
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Apolipoprotein A-I (Apo AI) Antibody

abx022327-1mg 1 mg
EUR 648
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Apolipoprotein A-I (Apo AI) Antibody

abx022328-1mg 1 mg
EUR 648
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Apolipoprotein A-I (Apo AI) Antibody

abx022329-1mg 1 mg
EUR 495
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Apolipoprotein A-I (Apo AI) Antibody

abx022330-1mg 1 mg
EUR 495
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Apolipoprotein A-I (Apo AI) Antibody

abx023211-1mg 1 mg
EUR 578
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Apolipoprotein A-I (Apo AI) Antibody

abx023214-1mg 1 mg
EUR 648
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Apolipoprotein A-I (Apo AI) Antibody

abx023215-05mg 0.5 mg
EUR 1135
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Apolipoprotein A-I (Apo AI) Antibody

abx023216-1ml 1 ml
EUR 467
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Apolipoprotein A-I (Apo AI) Antibody

abx023217-1ml 1 ml
EUR 425
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Apolipoprotein A-I (Apo AI) Antibody

abx023219-1ml 1 ml
EUR 509
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Apolipoprotein A-I (Apo AI) Antibody

abx023220-10ml 10 ml
EUR 439
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Apolipoprotein A-I (Apo AI) Antibody

abx023221-02mg 0.2 mg
EUR 509
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Apolipoprotein A-I (Apo-AI) Antibody

abx018162-100ug 100 ug
EUR 342
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Hamster apoprotein(apo-A1)ELISA Kit

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EUR 478

Hamster IgG, purified (Syrian, isotype control)

20003-1 1 mg
EUR 141

Hamster IgG, purified (Armenian, Isotype control)

20003-1AH 1 mg
EUR 263

Purified Hamster (syrian) serum albumin protein pure

ALBHS-15-N 1 mg
EUR 225

AI-3

B7761-10 10 mg
EUR 357

AI-3

B7761-50 50 mg
EUR 1340

Horse spleen Apo-ferritin purified, ELISA grade

FERT19-R-1000 1 mg
EUR 225

Purified Mouse Apo-Transferrin Protein (>98% pure)

TF14-N-1 1 mg
EUR 263

Hamster (Syrian, non-immune) Serum IgM, purified (Syrian)

20003-2-1 0.5 mg
EUR 225

Purified Rat Apo-Transferrin Protein WB +ve Control

TF12-C 100 ul
EUR 286

Purified Mouse Apo-Transferrin Protein WB +ve Control

TF14-C 100 ul
EUR 286

AI-10-49

HY-16786 10mg
EUR 257

AI-10-49

A8694-10 10 mg
EUR 212
Description: AI-10-49 is a selective inhibitor of CBF? -SMMHC and RUNX1 interaction with a FRET IC50 value of 260nM. AI-10-49 restores RUNX1 transcriptional activity, displays favorable pharmacokinetics, and delays leukemia progression in mice.

AI-10-49

A8694-25 25 mg
EUR 374
Description: AI-10-49 is a selective inhibitor of CBF? -SMMHC and RUNX1 interaction with a FRET IC50 value of 260nM. AI-10-49 restores RUNX1 transcriptional activity, displays favorable pharmacokinetics, and delays leukemia progression in mice.

AI-10-49

A8694-5 5 mg
EUR 142
Description: AI-10-49 is a selective inhibitor of CBF? -SMMHC and RUNX1 interaction with a FRET IC50 value of 260nM. AI-10-49 restores RUNX1 transcriptional activity, displays favorable pharmacokinetics, and delays leukemia progression in mice.

AI-10-49

A8694-5.1 10 mM (in 1mL DMSO)
EUR 305
Description: AI-10-49 is a selective inhibitor of CBF? -SMMHC and RUNX1 interaction with a FRET IC50 value of 260nM. AI-10-49 restores RUNX1 transcriptional activity, displays favorable pharmacokinetics, and delays leukemia progression in mice.

Human Apolipoprotein AI

STA-232 100 µg
EUR 450
Description:
  • Human Apolipoprotein AI. 100 µg.
  • Provided at a concentration of 1.0 mg/mL

anti- Apolipoprotein AI antibody

FNab00508 100µg
EUR 548.75
  • Immunogen: apolipoprotein A-I
  • Uniprot ID: P02647
  • Gene ID: 335
  • Research Area: Cardiovascular, Metabolism
Description: Antibody raised against Apolipoprotein AI

AI-BP Polyclonal Antibody

ES1613-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against AI-BP from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

AI-BP Polyclonal Antibody

ES1613-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against AI-BP from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

Human Apolipoprotein AI Protein

abx060864-1mg 1 mg
EUR 578
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Human Apolipoprotein AI Protein

abx060865-05mg 0.5 mg
EUR 384
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Human Apolipoprotein AI Protein

abx060867-1mg 1 mg
EUR 523
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AI-BP Polyclonal Antibody

ABP50614-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from the Internal region of human AI-BP at AA range: 90-170
  • Applications tips:
Description: A polyclonal antibody for detection of AI-BP from Human, Mouse, Rat. This AI-BP antibody is for WB , IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AI-BP at AA range: 90-170

AI-BP Polyclonal Antibody

ABP50614-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from the Internal region of human AI-BP at AA range: 90-170
  • Applications tips:
Description: A polyclonal antibody for detection of AI-BP from Human, Mouse, Rat. This AI-BP antibody is for WB , IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AI-BP at AA range: 90-170

AI-BP Polyclonal Antibody

ABP50614-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from the Internal region of human AI-BP at AA range: 90-170
  • Applications tips:
Description: A polyclonal antibody for detection of AI-BP from Human, Mouse, Rat. This AI-BP antibody is for WB , IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AI-BP at AA range: 90-170

Apolipoprotein AI (APOA1) Antibody

abx230508-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

Anti-Apolipoprotein AI antibody

PAab00508 100 ug
EUR 386

Anti-AI-BP antibody

STJ91512 200 µl
EUR 197
Description: Rabbit polyclonal to AI-BP.

Apolipoprotein AI, Human Plasma

P1521-100 100µg
EUR 227

AI M1 gene PCR kit

PCR-V603-48R 50T
EUR 524.4
  • Contact us in order to know the reactivity of the kit.
Description: An conventional PCR kit for detection of AI M1 gene

AI M1 gene PCR kit

PCR-V603-96R 100T
EUR 669.4
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Description: An conventional PCR kit for detection of AI M1 gene

Anti-HDL Apolipoprotein AI antibody

STJ16101187 1 mL
EUR 282

Anti-HDL Apolipoprotein AI antibody

STJ16101188 0.5 mg
EUR 381

Anti-HDL Apolipoprotein AI antibody

STJ16101199 1 mL
EUR 381

Anti-HDL Apolipoprotein AI antibody

STJ16101200 0.5 mg
EUR 381

Hamster IgM

31C-CH0707 1 mg
EUR 410
Description: Purified Hamster IgM

AI M1 gene RT PCR kit

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EUR 776.4
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Description: A Real-Time PCR kit for detection of AI M1 gene .

AI M1 gene RT PCR kit

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EUR 877.9
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Description: A Real-Time PCR kit for detection of AI M1 gene .

AI M1 gene RT PCR kit

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EUR 631.4
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Description: A Real-Time PCR kit for detection of AI M1 gene .

apo-B100/ Rat apo- B100 ELISA Kit

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apo-A1/ Rat apo- A1 ELISA Kit

ELA-E0604r 96 Tests
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Apo-E/ Rat Apo- E ELISA Kit

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Apo-E4/ Rat Apo- E4 ELISA Kit

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Hamster Mono Anti-Mouse CD3e IgG (Hamster IgG)

MCD003E-M 100 Tests
EUR 482

Hamster Mono Anti-Mouse CD3z IgG (Hamster IgG)

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Hamster CD28 Antibody

abx139999-01mg 0.1 mg
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Hamster CD3 Antibody

abx140000-01mg 0.1 mg
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Hamster CD3 Antibody

abx140001-01mg 0.1 mg
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Hamster CD80 Antibody

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Hamster CD154 Antibody

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Hamster Helios Antibody

abx140094-01mg 0.1 mg
EUR 411
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Hamster Complement Serum

32R-CH001 5 ml
EUR 424
Description: Purified normal Hamster Complement isolated from blood

Hamster Ig fraction

31R-1009 10 mg
EUR 138
Description: Hamster Ig fraction control or blocking reagent

Hamster Lymphocyte antibody

20R-LR011 20 mg
EUR 327
Description: Rabbit polyclonal Hamster Lymphocyte antibody

Hamster Lymphocyte antibody

20R-LR012 2 ml
EUR 241
Description: Rabbit polyclonal Hamster Lymphocyte antibody

Hamster RBC antibody

20R-RR021 20 mg
EUR 327
Description: Rabbit polyclonal Hamster RBC antibody

Hamster RBC antibody

20R-RR022 5 mg
EUR 554
Description: Rabbit polyclonal Hamster RBC antibody

Hamster IgG (FITC)

65C-CH0702 1 mg
EUR 200
Description: Purified Hamster IgG FITC conjugate

Hamster IgG (HRP)

65C-CH0703 1 mg
EUR 247
Description: Purified Hamster IgG HRP conjugate

Recombinant Hamster Uter

P0138 100ug
EUR 522.36
  • Formulation: pH7.4, Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose
  • Reconstitution: Sterile distilled water
  • Purity: Greater than 95% by SDS-PAGE gel analyses
  • Uniprot ID: Q8VD96
Description: Recombinant Hamster protein for Uter

Hamster Transthyretin (TTR)

QY-E90097 96T
EUR 478

Human apo-Serum Amyloid A1 (apo-SAA1) Protein

abx670232-50ug 50 ug
EUR 565
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Clusterin/Apo J

GT15117 100 ug
EUR 526

Apo AII Protein

abx069752-05mg 0.5 mg
EUR 384
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Apo E Protein

abx069753-005mg 0.05 mg
EUR 467
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Apo H Protein

abx069757-1mg 1 mg
EUR 1295
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Apo Transferrin Peptide

abx260006-1gr 1 gr
EUR 648
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Apo Transferrin Peptide

abx260006-500mg 500 mg
EUR 467
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Apo Transferrin Peptide

abx260006-5grs 5 grs
EUR 2082
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APO-D Protein

20-abx263521
  • EUR 829.00
  • EUR 411.00
  • EUR 537.00
  • 10 ug
  • 2 µg
  • 5 ug
  • Shipped within 5-10 working days.

Apo-J/Clusterin

4325-10
EUR 349

Apo-J/Clusterin

4325-500
EUR 7814

Transferrin protein (Apo)

30R-AT019 1 gram
EUR 553
Description: Purified native Human Transferrin protein (Apo)

Lactoferrin protein (Apo)

30-1146L 5 mg
EUR 298
Description: Purified native Human Lactoferrin protein

Transferrin Apo protein

30-1222 100 mg
EUR 299
Description: Purified native Human Transferrin Apo protein

Apo SAA antibody

20R-1792 100 ug
EUR 673
Description: Rabbit polyclonal Apo SAA antibody

Apo (a) antibody

20-AG73 10 ml
EUR 246
Description: Goat polyclonal Apo (a) antibody

Human Apo Transferrin

7-04408 500mg Ask for price

Human Apo Transferrin

7-04409 1gram Ask for price

Human Apo Transferrin

7-04410 5grams Ask for price

Bovine Apo Transferrin

7-04411 500mg Ask for price

Bovine Apo Transferrin

7-04412 1gram Ask for price

Bovine Apo Transferrin

7-04413 5grams Ask for price

Apo Transferrin (ATF)

PR27104 500 mg
EUR 435

Clusterin/APO-J

PR27111 2 ug
EUR 191

Apo-12'-lycopenal

TBW00395 5mg
EUR 484

Human Apolipoprotein AI / B Calibrator 3 Protein

abx060868-10ml 10 ml
EUR 676
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Human Apolipoprotein AI / B Free Serum Protein

abx060869-100ml 100 ml
EUR 495
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AI M1 gene One-Step PCR kit

Oneq-V603-100R 100T
EUR 933
  • Contact us in order to know the reactivity of the kit.
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of AI M1 gene.

AI M1 gene One-Step PCR kit

Oneq-V603-150R 150T
EUR 1060.6
  • Contact us in order to know the reactivity of the kit.
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of AI M1 gene.

AI M1 gene One-Step PCR kit

Oneq-V603-50R 50T
EUR 751.75
  • Contact us in order to know the reactivity of the kit.
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of AI M1 gene.

Goat Anti-Human Apolipoprotein AI Polyclonal Antibody

STA-132 100 µg
EUR 496
Description: Goat Anti-Human Apolipoprotein AI Polyclonal Antibody is Affinity purified and suitable for Western blot or ELISA. 100 µg.

Hamster Mono Anti-Mouse CD25 , Pur. Low Endotoxin (Hamster IgG)

MCD027-M 100 ug
EUR 482

Non-sterile hamster serum

HAS05-0050 50 ml
EUR 257.4
  • Non-sterile hamster serum is indicated as RUO. Do not use on humans.

Non-sterile hamster serum

HAS05-0100 100 ml
EUR 327.6
  • Non-sterile hamster serum is indicated as RUO. Do not use on humans.

Non-sterile hamster serum

HAS05-0500 500 ml
EUR 603.2
  • Non-sterile hamster serum is indicated as RUO. Do not use on humans.

Hamster CD3 Antibody (PerCP)

abx140002-01mg 0.1 mg
EUR 398
  • Shipped within 5-12 working days.

Hamster CD3 Antibody (PE)

abx140003-01mg 0.1 mg
EUR 328
  • Shipped within 5-12 working days.

Hamster CD3 Antibody (APC)

abx140004-01mg 0.1 mg
EUR 370
  • Shipped within 5-12 working days.

Hamster CD3 Antibody (Biotin)

abx140005-01mg 0.1 mg
EUR 272
  • Shipped within 5-12 working days.

Hamster CD3 Antibody (FITC)

abx140006-01mg 0.1 mg
EUR 314
  • Shipped within 5-12 working days.

Hamster CD154 Antibody (FITC)

abx140093-01mg 0.1 mg
EUR 537
  • Shipped within 5-12 working days.

Hamster Helios Antibody (PE)

abx140095-100tests 100 tests
EUR 537
  • Shipped within 5-12 working days.

Hamster Anti CD28 Antibody

20-abx137056
  • EUR 356.00
  • EUR 523.00
  • 0.5 mg
  • 1 mg
  • Shipped within 5-10 working days.

Normal Syrian Hamster Serum

88R-1018 5 ml
EUR 173
Description: Normal Syrian Hamster Serum which has been lipid extracted and dialyzed against 10 mM Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Hamster Red Blood Cells

88R-H001 5 ml
EUR 273
Description: Glutaraldehyde-stabilized freshly prepared Hamster Red Blood Cells

Hamster Red Blood Cells

88R-H003 10 ml
EUR 489
Description: Washed and freshly prepared 10% suspension of Hamster Red Blood Cells

Hamster Lymphocyte antibody (FITC)

60R-LR001FT 2 mg
EUR 365
Description: Rabbit polyclonal Hamster Lymphocyte antibody (FITC) conjugated

Hamster RBC antibody (FITC)

60R-RR021FT 3 mg
EUR 392
Description: Rabbit polyclonal Hamster RBC antibody (FITC) conjugated

Genomic DNA - Hamster Male

D1H34999-G01 100 ug
EUR 188
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Genomic DNA - Hamster Female

D1H34999-G02 100 ug
EUR 188
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Recombinant Hamster IL-10

P0539 100ug
EUR 522.36
  • Formulation: pH7.4, Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose
  • Reconstitution: Sterile distilled water
  • Purity: Greater than 95% by SDS-PAGE gel analyses
  • Uniprot ID: G3HB01
Description: Recombinant Hamster protein for IL-10

Hamster Cortisol ELISA Kit

QY-E90073 96T
EUR 478

Hamster Notch1 ELISA Kit

QY-E90124 96T
EUR 478

Antibody for Hamster HSP110

SPC-195C 0.025mg
EUR 174
  • HSP110 belongs to a family of large stress proteins known as the HSP110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied HSP70 family. They share 30-33% amino acid identity, mostly in the conserved AT
  • Show more
Description: A polyclonal antibody for HSP110 from Human | Mouse | Rat | Bovine | Monkey | Hamster | Sheep | Yeast | Shark | Gummy Shark (Mustelus antarcticus) | School Shark (Galeorhinus galeus) . The antibody is produced in rabbit after immunization with Hamster Synthetic peptide derived from the sequence of hamster HSP110; sequence identical to human and mouse. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This HSP110 antibody is unconjugated.

Antibody for Hamster HSP110

SPC-195D 0.1mg
EUR 306
  • HSP110 belongs to a family of large stress proteins known as the HSP110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied HSP70 family. They share 30-33% amino acid identity, mostly in the conserved AT
  • Show more
Description: A polyclonal antibody for HSP110 from Human | Mouse | Rat | Bovine | Monkey | Hamster | Sheep | Yeast | Shark | Gummy Shark (Mustelus antarcticus) | School Shark (Galeorhinus galeus) . The antibody is produced in rabbit after immunization with Hamster Synthetic peptide derived from the sequence of hamster HSP110; sequence identical to human and mouse. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This HSP110 antibody is unconjugated.

Antibody for Hamster HSP110

SPC-195D-A390 0.1mg
EUR 353
  • HSP110 belongs to a family of large stress proteins known as the HSP110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied HSP70 family. They share 30-33% amino acid identity, mostly in the conserved AT
  • Show more
Description: A polyclonal antibody for HSP110 from Human | Mouse | Rat | Bovine | Monkey | Hamster | Sheep | Yeast | Shark | Gummy Shark (Mustelus antarcticus) | School Shark (Galeorhinus galeus) . The antibody is produced in rabbit after immunization with Hamster Synthetic peptide derived from the sequence of hamster HSP110; sequence identical to human and mouse. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This HSP110 antibody is conjugated to ATTO 390.

Antibody for Hamster HSP110

SPC-195D-A488 0.1mg
EUR 352
  • HSP110 belongs to a family of large stress proteins known as the HSP110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied HSP70 family. They share 30-33% amino acid identity, mostly in the conserved AT
  • Show more
Description: A polyclonal antibody for HSP110 from Human | Mouse | Rat | Bovine | Monkey | Hamster | Sheep | Yeast | Shark | Gummy Shark (Mustelus antarcticus) | School Shark (Galeorhinus galeus) . The antibody is produced in rabbit after immunization with Hamster Synthetic peptide derived from the sequence of hamster HSP110; sequence identical to human and mouse. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This HSP110 antibody is conjugated to ATTO 488.

Antibody for Hamster HSP110

SPC-195D-A565 0.1mg
EUR 352
  • HSP110 belongs to a family of large stress proteins known as the HSP110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied HSP70 family. They share 30-33% amino acid identity, mostly in the conserved AT
  • Show more
Description: A polyclonal antibody for HSP110 from Human | Mouse | Rat | Bovine | Monkey | Hamster | Sheep | Yeast | Shark | Gummy Shark (Mustelus antarcticus) | School Shark (Galeorhinus galeus) . The antibody is produced in rabbit after immunization with Hamster Synthetic peptide derived from the sequence of hamster HSP110; sequence identical to human and mouse. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This HSP110 antibody is conjugated to ATTO 565.

Antibody for Hamster HSP110

SPC-195D-A594 0.1mg
EUR 352
  • HSP110 belongs to a family of large stress proteins known as the HSP110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied HSP70 family. They share 30-33% amino acid identity, mostly in the conserved AT
  • Show more
Description: A polyclonal antibody for HSP110 from Human | Mouse | Rat | Bovine | Monkey | Hamster | Sheep | Yeast | Shark | Gummy Shark (Mustelus antarcticus) | School Shark (Galeorhinus galeus) . The antibody is produced in rabbit after immunization with Hamster Synthetic peptide derived from the sequence of hamster HSP110; sequence identical to human and mouse. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This HSP110 antibody is conjugated to ATTO 594.

Antibody for Hamster HSP110

SPC-195D-A633 0.1mg
EUR 352
  • HSP110 belongs to a family of large stress proteins known as the HSP110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied HSP70 family. They share 30-33% amino acid identity, mostly in the conserved AT
  • Show more
Description: A polyclonal antibody for HSP110 from Human | Mouse | Rat | Bovine | Monkey | Hamster | Sheep | Yeast | Shark | Gummy Shark (Mustelus antarcticus) | School Shark (Galeorhinus galeus) . The antibody is produced in rabbit after immunization with Hamster Synthetic peptide derived from the sequence of hamster HSP110; sequence identical to human and mouse. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This HSP110 antibody is conjugated to ATTO 633.

Antibody for Hamster HSP110

SPC-195D-A655 0.1mg
EUR 352
  • HSP110 belongs to a family of large stress proteins known as the HSP110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied HSP70 family. They share 30-33% amino acid identity, mostly in the conserved AT
  • Show more
Description: A polyclonal antibody for HSP110 from Human | Mouse | Rat | Bovine | Monkey | Hamster | Sheep | Yeast | Shark | Gummy Shark (Mustelus antarcticus) | School Shark (Galeorhinus galeus) . The antibody is produced in rabbit after immunization with Hamster Synthetic peptide derived from the sequence of hamster HSP110; sequence identical to human and mouse. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This HSP110 antibody is conjugated to ATTO 655.

Antibody for Hamster HSP110

SPC-195D-A680 0.1mg
EUR 352
  • HSP110 belongs to a family of large stress proteins known as the HSP110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied HSP70 family. They share 30-33% amino acid identity, mostly in the conserved AT
  • Show more
Description: A polyclonal antibody for HSP110 from Human | Mouse | Rat | Bovine | Monkey | Hamster | Sheep | Yeast | Shark | Gummy Shark (Mustelus antarcticus) | School Shark (Galeorhinus galeus) . The antibody is produced in rabbit after immunization with Hamster Synthetic peptide derived from the sequence of hamster HSP110; sequence identical to human and mouse. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This HSP110 antibody is conjugated to ATTO 680.

Antibody for Hamster HSP110

SPC-195D-A700 0.1mg
EUR 352
  • HSP110 belongs to a family of large stress proteins known as the HSP110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied HSP70 family. They share 30-33% amino acid identity, mostly in the conserved AT
  • Show more
Description: A polyclonal antibody for HSP110 from Human | Mouse | Rat | Bovine | Monkey | Hamster | Sheep | Yeast | Shark | Gummy Shark (Mustelus antarcticus) | School Shark (Galeorhinus galeus) . The antibody is produced in rabbit after immunization with Hamster Synthetic peptide derived from the sequence of hamster HSP110; sequence identical to human and mouse. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This HSP110 antibody is conjugated to ATTO 700.

Antibody for Hamster HSP110

SPC-195D-ALP 0.1mg
EUR 346
  • HSP110 belongs to a family of large stress proteins known as the HSP110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied HSP70 family. They share 30-33% amino acid identity, mostly in the conserved AT
  • Show more
Description: A polyclonal antibody for HSP110 from Human | Mouse | Rat | Bovine | Monkey | Hamster | Sheep | Yeast | Shark | Gummy Shark (Mustelus antarcticus) | School Shark (Galeorhinus galeus) . The antibody is produced in rabbit after immunization with Hamster Synthetic peptide derived from the sequence of hamster HSP110; sequence identical to human and mouse. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This HSP110 antibody is conjugated to Alkaline Phosphatase.

Antibody for Hamster HSP110

SPC-195D-APC 0.1mg
EUR 351
  • HSP110 belongs to a family of large stress proteins known as the HSP110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied HSP70 family. They share 30-33% amino acid identity, mostly in the conserved AT
  • Show more
Description: A polyclonal antibody for HSP110 from Human | Mouse | Rat | Bovine | Monkey | Hamster | Sheep | Yeast | Shark | Gummy Shark (Mustelus antarcticus) | School Shark (Galeorhinus galeus) . The antibody is produced in rabbit after immunization with Hamster Synthetic peptide derived from the sequence of hamster HSP110; sequence identical to human and mouse. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This HSP110 antibody is conjugated to APC .

Antibody for Hamster HSP110

SPC-195D-APCCY7 0.1mg
EUR 423
  • HSP110 belongs to a family of large stress proteins known as the HSP110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied HSP70 family. They share 30-33% amino acid identity, mostly in the conserved AT
  • Show more
Description: A polyclonal antibody for HSP110 from Human | Mouse | Rat | Bovine | Monkey | Hamster | Sheep | Yeast | Shark | Gummy Shark (Mustelus antarcticus) | School Shark (Galeorhinus galeus) . The antibody is produced in rabbit after immunization with Hamster Synthetic peptide derived from the sequence of hamster HSP110; sequence identical to human and mouse. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This HSP110 antibody is conjugated to APC/Cy7.

Antibody for Hamster HSP110

SPC-195D-BI 0.1mg
EUR 348
  • HSP110 belongs to a family of large stress proteins known as the HSP110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied HSP70 family. They share 30-33% amino acid identity, mostly in the conserved AT
  • Show more
Description: A polyclonal antibody for HSP110 from Human | Mouse | Rat | Bovine | Monkey | Hamster | Sheep | Yeast | Shark | Gummy Shark (Mustelus antarcticus) | School Shark (Galeorhinus galeus) . The antibody is produced in rabbit after immunization with Hamster Synthetic peptide derived from the sequence of hamster HSP110; sequence identical to human and mouse. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This HSP110 antibody is conjugated to Biotin.

Antibody for Hamster HSP110

SPC-195D-DY350 0.1mg
EUR 366
  • HSP110 belongs to a family of large stress proteins known as the HSP110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied HSP70 family. They share 30-33% amino acid identity, mostly in the conserved AT
  • Show more
Description: A polyclonal antibody for HSP110 from Human | Mouse | Rat | Bovine | Monkey | Hamster | Sheep | Yeast | Shark | Gummy Shark (Mustelus antarcticus) | School Shark (Galeorhinus galeus) . The antibody is produced in rabbit after immunization with Hamster Synthetic peptide derived from the sequence of hamster HSP110; sequence identical to human and mouse. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This HSP110 antibody is conjugated to Dylight 350.

Antibody for Hamster HSP110

SPC-195D-DY405 0.1mg
EUR 355
  • HSP110 belongs to a family of large stress proteins known as the HSP110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied HSP70 family. They share 30-33% amino acid identity, mostly in the conserved AT
  • Show more
Description: A polyclonal antibody for HSP110 from Human | Mouse | Rat | Bovine | Monkey | Hamster | Sheep | Yeast | Shark | Gummy Shark (Mustelus antarcticus) | School Shark (Galeorhinus galeus) . The antibody is produced in rabbit after immunization with Hamster Synthetic peptide derived from the sequence of hamster HSP110; sequence identical to human and mouse. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This HSP110 antibody is conjugated to Dylight 405.

Antibody for Hamster HSP110

SPC-195D-DY488 0.1mg
EUR 345
  • HSP110 belongs to a family of large stress proteins known as the HSP110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied HSP70 family. They share 30-33% amino acid identity, mostly in the conserved AT
  • Show more
Description: A polyclonal antibody for HSP110 from Human | Mouse | Rat | Bovine | Monkey | Hamster | Sheep | Yeast | Shark | Gummy Shark (Mustelus antarcticus) | School Shark (Galeorhinus galeus) . The antibody is produced in rabbit after immunization with Hamster Synthetic peptide derived from the sequence of hamster HSP110; sequence identical to human and mouse. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This HSP110 antibody is conjugated to Dylight 488.

Antibody for Hamster HSP110

SPC-195D-DY594 0.1mg
EUR 347
  • HSP110 belongs to a family of large stress proteins known as the HSP110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied HSP70 family. They share 30-33% amino acid identity, mostly in the conserved AT
  • Show more
Description: A polyclonal antibody for HSP110 from Human | Mouse | Rat | Bovine | Monkey | Hamster | Sheep | Yeast | Shark | Gummy Shark (Mustelus antarcticus) | School Shark (Galeorhinus galeus) . The antibody is produced in rabbit after immunization with Hamster Synthetic peptide derived from the sequence of hamster HSP110; sequence identical to human and mouse. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This HSP110 antibody is conjugated to Dylight 594.

Antibody for Hamster HSP110

SPC-195D-DY633 0.1mg
EUR 342
  • HSP110 belongs to a family of large stress proteins known as the HSP110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied HSP70 family. They share 30-33% amino acid identity, mostly in the conserved AT
  • Show more
Description: A polyclonal antibody for HSP110 from Human | Mouse | Rat | Bovine | Monkey | Hamster | Sheep | Yeast | Shark | Gummy Shark (Mustelus antarcticus) | School Shark (Galeorhinus galeus) . The antibody is produced in rabbit after immunization with Hamster Synthetic peptide derived from the sequence of hamster HSP110; sequence identical to human and mouse. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This HSP110 antibody is conjugated to Dylight 633.

Antibody for Hamster HSP110

SPC-195D-FITC 0.1mg
EUR 344
  • HSP110 belongs to a family of large stress proteins known as the HSP110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied HSP70 family. They share 30-33% amino acid identity, mostly in the conserved AT
  • Show more
Description: A polyclonal antibody for HSP110 from Human | Mouse | Rat | Bovine | Monkey | Hamster | Sheep | Yeast | Shark | Gummy Shark (Mustelus antarcticus) | School Shark (Galeorhinus galeus) . The antibody is produced in rabbit after immunization with Hamster Synthetic peptide derived from the sequence of hamster HSP110; sequence identical to human and mouse. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This HSP110 antibody is conjugated to FITC.

Antibody for Hamster HSP110

SPC-195D-HRP 0.1mg
EUR 340
  • HSP110 belongs to a family of large stress proteins known as the HSP110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied HSP70 family. They share 30-33% amino acid identity, mostly in the conserved AT
  • Show more
Description: A polyclonal antibody for HSP110 from Human | Mouse | Rat | Bovine | Monkey | Hamster | Sheep | Yeast | Shark | Gummy Shark (Mustelus antarcticus) | School Shark (Galeorhinus galeus) . The antibody is produced in rabbit after immunization with Hamster Synthetic peptide derived from the sequence of hamster HSP110; sequence identical to human and mouse. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This HSP110 antibody is conjugated to HRP.

Antibody for Hamster HSP110

SPC-195D-P594 0.1mg
EUR 359
  • HSP110 belongs to a family of large stress proteins known as the HSP110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied HSP70 family. They share 30-33% amino acid identity, mostly in the conserved AT
  • Show more
Description: A polyclonal antibody for HSP110 from Human | Mouse | Rat | Bovine | Monkey | Hamster | Sheep | Yeast | Shark | Gummy Shark (Mustelus antarcticus) | School Shark (Galeorhinus galeus) . The antibody is produced in rabbit after immunization with Hamster Synthetic peptide derived from the sequence of hamster HSP110; sequence identical to human and mouse. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This HSP110 antibody is conjugated to PE/ATTO 594.

Antibody for Hamster HSP110

SPC-195D-PCP 0.1mg
EUR 351
  • HSP110 belongs to a family of large stress proteins known as the HSP110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied HSP70 family. They share 30-33% amino acid identity, mostly in the conserved AT
  • Show more
Description: A polyclonal antibody for HSP110 from Human | Mouse | Rat | Bovine | Monkey | Hamster | Sheep | Yeast | Shark | Gummy Shark (Mustelus antarcticus) | School Shark (Galeorhinus galeus) . The antibody is produced in rabbit after immunization with Hamster Synthetic peptide derived from the sequence of hamster HSP110; sequence identical to human and mouse. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This HSP110 antibody is conjugated to PerCP.

Antibody for Hamster HSP110

SPC-195D-RPE 0.1mg
EUR 349
  • HSP110 belongs to a family of large stress proteins known as the HSP110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied HSP70 family. They share 30-33% amino acid identity, mostly in the conserved AT
  • Show more
Description: A polyclonal antibody for HSP110 from Human | Mouse | Rat | Bovine | Monkey | Hamster | Sheep | Yeast | Shark | Gummy Shark (Mustelus antarcticus) | School Shark (Galeorhinus galeus) . The antibody is produced in rabbit after immunization with Hamster Synthetic peptide derived from the sequence of hamster HSP110; sequence identical to human and mouse. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This HSP110 antibody is conjugated to RPE .

События ускорения обычно подвергают военных пилотов потенциально опасным ускорениям + Gz (осевое, от каудального до краниального). Лаборатория морской биодинамики подвергала нечеловеческих приматов (NHP) нагрузке + Gz в двух ориентациях испытуемых (лежа на спине или стоя), чтобы оценить влияние ориентации и ускорений, связанных с травмами при ускорениях, небезопасных для участия человека.

Для выявления травм, связанных с ускорением, использовались архивные записи об оказании помощи, отчеты о пробежках, а также отчеты о вскрытии и патологии. Травмы были разделены на центральную нервную систему (ЦНС), скелетно-мышечную систему (MSK) и грудную клетку (THR). Сравнивали возникновение травм относительно соответствующего пикового ускорения салазок (ПСА) и ориентации испытуемого. Для каждой категории травм применялся t-критерий, чтобы проверить значительную разницу в среднем уровне ПСА между ориентациями.

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